HALIFAX – Executives of DHX Media told its annual shareholders meeting in Halifax that they expect a strategic review of its options to be complete by June 30, at the end of its fiscal fourth-quarter and 2018 financial year.Executive chairman Michael Donovan said DHX is evaluating multiple promising opportunities that he hopes will have a positive effect on the company’s share price.He made the comment in response to a complaint about the DHX share price, which was described as “floundering.”DHX Media shares opened at $4.01 at the Toronto Stock Exchange as the meeting was being held, about 26 per cent lower than it was a year ago and 45 per cent below its 52-week high in September.Donovan and David Regan, the company’s executive vice-president for strategy and corporate development, said they were confident that the company’s financial performance will be improved by initiatives taken over the past year.The biggest of these was the acquisition of rights to the Peanuts cartoon franchise, in a US$345-million deal that DHX management believes will create multiple opportunities to add to the company’s kid-oriented revenue streams.Companies in this story: (TSX:DHX.B)
HOUSTON — Students are returning to school in an area southeast of Houston after a fire at a petrochemical storage facility prompted several days of cancelled classes.Students were back in class Monday in Deer Park, Galena Park and other communities near the International Terminals Company in Deer Park. Classes were cancelled because of concerns over air quality near the facility, which caught fire on March 17 and burned for several days.The fire destroyed or damaged storage tanks that contained components of gasoline and materials used in nail polish remover, glues and paint thinner. Elevated levels of benzene were detected in the air Thursday, prompting officials to order people to remain indoors.The fire also led to the closure of part of the Houston Ship Channel. The U.S. Coast Guard says it hopes to have the channel reopened Monday.The Associated Press
The foundation, which has been named after Lyca Group chairman Subaskaran Allirajah’s mother, has constructed these homes at a cost of 22 crore. The foundation has been working extensively in the northern and eastern regions of Sri Lanka to rebuild schools that were destroyed in the civil war in 2009. When asked about the project, Raju Mahalingam, creative head, Lyca Productions, said that the entire project has been completed in a period of one-and-a-half years. “ After MGR, no mass hero of that stature has visited and spoken in Jaffna,” he added. These homes have been built in Chinna Tampan and Puliyankulam regions in northern Sri Lanka.On April 10, Rajinikanth will be in Vavuniya to unveil the new homes and he will also plant tree saplings. A press statement released by Lyca Productions said that C.V. Vigneswaran, Chief Minister, Northern Province, Tamil National Alliance leader R. Sampanthan, Malaysian Senate leader S. Vigneswaran, British all-party parliamentary Tamil council’s leader James Ferry and Justice Committee member Keith Vaz will be present at the presentation ceremony. Actor Rajinikanth will hand over to Tamils, the keys to 150 homes built for them by Gnanam Foundation on April 9 in Jaffna, The Hindu newspaper reported.While the rehabilitation of displaced Tamils is still a contentious issue, Rajinikanth’s visit to Jaffna is likely to attract a huge crowd as he is also expected to speak at a public meeting in Jaffna. The actor is starring in Lyca Productions’ film 2.0, expected to be released during Deepavali. (Colombo Gazette)
As home prices soar, some first-time buyers reconsider home ownership dreams TORONTO – Earlier this year, Meghan Morrison and her fiance made the difficult decision to add two hours of commuting onto their day in order to pursue their dream of owning a house.The couple could have purchased a condo in the Toronto area, where they both work, but Morrison says they wanted more space to be able to engage in their hobbies and, eventually, start a family.“We looked at new builds in Toronto and it’s just like, oh my gosh, $400,000 for 600 square feet,” says Morrison, 26.In January, the couple will be moving into their newly purchased, two-storey brick home in Barrie, Ont., complete with a two-car garage and a large, fenced-in yard for their French bulldog to play in.“It was a really tough decision,” Morrison says. “We struggled with it for a long time. But we just couldn’t see ourselves living in a condo forever.”With home prices in Toronto, Vancouver and their surrounding areas soaring increasingly out of reach, many first-time buyers are being forced to either move out of the city or reconsider their home ownership dreams.But in oil-producing provinces such as Alberta, Saskatchewan and Newfoundland — where the plummet in the price of crude has hampered economic growth — the picture is starkly different.Phil Soper, president of Royal LePage, says sales volumes are down about 20 per cent in Alberta from their long-term average.“The regional disparities are as great as I’ve ever seen them,” Soper says.“Depending on your views, it was one of the toughest years in the housing market since the Great Recession, or it’s crazy overheated and the government should step in and do something about it.”CIBC deputy chief economist Benjamin Tal predicts softer markets in Toronto and Vancouver in the year ahead, as government changes — including the 15 per cent tax on foreign buyers in Vancouver and federal mortgage rules changes — are felt.Both the B.C. and Ontario governments have also announced efforts lately to help first-time buyers get into the market.The B.C. government launched a plan to offer loans to help first-time homebuyers get into the real estate market. The loans are interest-free and payment-free for the first five years.“Clearly 2016 has been, from a policy perspective, a very important year that will impact the trajectory of the housing market in the coming years,” Tal said.Soper says price growth is expected to slow in the Greater Toronto Area, and possibly reverse in Vancouver, but there could be a return to moderate growth in Alberta and other oil-producing regions.The new mortgage rules introduced by Ottawa in October, which require all insured mortgages to undergo a stress test, will likely cause some would-be buyers to keep renting instead, Tal said.“I do think that the rental market will be even tighter,” he said.That could spell trouble for people like Nicole Silver, a 23-year-old marketing and public relations professional in the Toronto area.After spending years living at home with her family to save money, Silver was ready to put down a $60,000 to $70,000 down payment on a condo this fall.But she soon discovered that even condo prices had climbed out of her reach.“If I had done this a little bit earlier, like a couple of months earlier, maybe it would have been better,” Silver says. “I feel like every month it’s getting worse and worse.”Although she’s still keeping an eye on the market, Silver says she’s more or less resigned herself to renting.“I don’t want to just be paying rent to live in someone else’s home,” she says. “I’m not very happy with that, but it’s just the reality.”Heather Rollwagen, assistant professor of sociology at Ryerson University, says home ownership is important to many Canadians because it’s culturally constructed as economic security.“I think people are kind of told that renting is irresponsible somehow,” Rollwagen says.However, buying a property is not necessarily more economically secure, Rollwagen says — particularly for lower income earners who take on large debts and therefore become vulnerable to changes in interest rates.“I’m eager to see, over the next 10 or 15 years, how millennials’ attitudes are going to drive changes in the value of home ownership, because they’re the ones that are really starting to opt out,” she says.Follow @alexposadzki on Twitter. Nicole Silver is pictured in a Toronto condo development, on Saturday December 17, 2016. After spending years living at home with her family to save money, Silver was ready to put down a $60,000 to $70,000 down payment on a condo this fall. But she soon discovered that even condo prices had climbed out of her reach.THE CANADIAN PRESS/Chris Young by Alexandra Posadzki, The Canadian Press Posted Dec 16, 2016 8:00 am MDT Last Updated Dec 17, 2016 at 6:20 pm MDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email
Anyone who witnessed the incident, or who knows the identity of the men, is asked to contact BTP by texting 61016 or by calling 0800 40 50 40 quoting reference 171 of 20/07/19. Know them? Gas was released on a tube carriage at Oxford Circus this morning. People were treated at the scene for coughing etc. No further health concerns.Symptoms suggest the gas was CS gas. Text us on 61016 quoting ref 171 of 20/07/19.More info: https://t.co/AExTbznYdr pic.twitter.com/c9olq5JCyl— BTP London (@BTPLondon) July 20, 2019 Police are hunting for two men after gas was released on a Tube train in central London on Saturday.British Transport Police (BTP) confirmed that the incident was reported at 9.13am.A number of people were treated at the scene at Oxford Circus by paramedics for coughing and lack of breath.There are no further concerns for their health.BTP added that their symptoms “would suggest the gas is CS gas”.Officers hunting for the perpetrators have released CCTV images of two young white men they want to trace after the incident, which was reported at 9.13am. Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily Front Page newsletter and new audio briefings.
Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily Front Page newsletter and new audio briefings. A man has died and another is in hospital after a stabbing on Camden High Street, police say.Officers were called just after 11pm on Thursday and found a man with a stab injury who was given first aid but was pronounced dead at the scene, Scotland Yard said.No other details about the man were immediately available.A second man, aged in his mid-20s, was found nearby also with a stab injury, and has been taken to a central London hospital.No arrests have yet been made and police asked anyone with information to call them on 101 quoting reference Cad 8865/12Sep.Alternatively, they can call Crimestoppers anonymously on 0800 555 111.Police said a Section 60 order – which allows officers to stop and search anyone – had been authorised for the borough of Camden.
The Guyana Power and Light (GPL) linesman, who suffered from an electric shock on May 15, 2018 in the vicinity of the Stabroek Square while conducting line maintenance work, is pleading with the power company for some form of compensation, since it was while executing the company’s duties he suffered severe injuries.Dara Singh is pleading for assistance to provide for his familyReports reaching INews indicated that the victim, Dara Singh, 41, is unable to walk, but he is slowly recovering.According to the man’s wife Maureen Katow-Singh, the doctors told her that the linesman would have to undergo yet another surgery since he received first degree burns to the skull and almost 80 percent of his body.Singh, who spoke from his hospital bed, related that the company only signed an agreement to give his wife passage to travel from their Garden of Eden, East Bank Demerara home to the hospital.The woman related that the father of three is the sole breadwinner for his family; and they are presently unable to send their children to school following the incident.She further related that all she wants is for the company to look into their plight and give them some sort of assistance.Efforts to get a comment from the company’s Public Relations Officer Shevon Sears on the matter proved futile.Singh, who has been working with the power company for the past 12 years, was at the time of the incident holding wires, which suddenly became live, thus pelting him a few feet backwards.He reportedly landed on his back with the wires resting across his stomach. Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)RelatedGPL worker falls off rotten pole, diesJanuary 5, 2017In “Local News”GPL linesman ‘slowly recovering’ following electric shockMay 15, 2018In “latest news”Mon Repos family traumatised following home invasion, robbery by banditsNovember 27, 2016In “Crime”
A MAN HAS died in an accident at University College Cork.Gardaí told TheJournal.ie that the man in his 50s was fatally injured during an industrial-type accident. The man and a second person were at the scene when the incident occurred.It is believed the man was on a cherry picker when he was injured this afternoon on campus.He was pronounced dead at the scene and brought to Cork University Hospital. A post-mortem is due to take place.The Health and Safety Authority and gardaí are investigating.The Cork Independent reports that the man was an employee at UCC.
Thoughts of SkyNet pass through my head every time I hear about the Google Car. This nearly self-aware car has on-board tech that allows someone to sit in the passenger seat as the car drives for them. And that’s not even the coolest part: there’s a ton of really neat gear in this car including a giant spinning top on the roof, which acts like an echo-location like system for detecting the world around it. Google had one of these cars on display at the Infinite Playground setup during the Google I/O afterparty!These cars use video cameras, radar sensors and a laser range finder to “see” other traffic, as well as detailed maps (which they collect using manually driven vehicles) to navigate the road ahead. This is all made possible by Google’s data centers, which can process the enormous amounts of information gathered by our cars when mapping streets. In fact, Google even had a monitor up, to show off what the car could “see” in a room full over thousands of people.There’s a ton of data just on this screen, and its all in realtime. For example, if you are standing next to the car and wave your hand you can see the radar image of yourself on the screen. From the nose of the car, the yellow light extends just about 50 feet, and the car can detect those bodies nearly to the stage. It’s also able to see in 3D, as evidenced by the speaker above the stage highlighted in yellow.According to Google, the cars still require someone in the drivers seat, but only as a “just in case” measure. When these cars are allowed on the streets of Nevada, Google will be able to harvest massive amounts of topographical data, and way more. Imagine if your car can detect a pothole, avoid it, and then email a road maintenance crew to alert them that the issue exists.So, to recap, this week Google showed us their Android @ Home project where the house will eventually be controlled by our phones, and now we’ve seen how these self-driving cars work. I’m not sure whether to praise the implementer of the great Isaac Asimov, or curse the inventor of Skynet.See our previous coverage of the Google Car.
Dozens of secondary school teachers appointed to work in the Greek Islands have found themselves sleeping in their cars or on the beach, falling victim to the extended tourism season.Schools in rural and remote areas of Greece depend on temporary, seasonal employees and younger teachers often find themselves travelling around Greece looking for lodging each September. However, as this year’s tourist season lingers on, the available rooms are fewer and pricier – especially in islands such as Mykonos and Santorini. Complaints made public through the website of PAME, the communist-party-controlled workers’ union, state that teachers have been asked to pay anything from €350 to €700 per month for a one- or two-bedroom apartment, when the monthly salary of a temp teacher does not exceed €850.Part of the problem is an effect of the last-minute announcement of their employment. According to a report printed in Ta Nea newspaper, the Education Ministry hired 15,000 teachers in just two days, without consulting with local councils as to where they will stay once they arrive at their place of hire. Facebook Twitter: @NeosKosmos Instagram
Fast-foods : ils pourront rester près des écolesFrance – Le Parlement a repoussé hier, jeudi 1er juillet, la proposition du Nouveau Centre qui visait à éloigner les fast-foods des écoles.Avec le projet sur la modernisation de l’agriculture, il a semblé important à deux députés centristes, messieurs Jean Dionis et Philippe Folliot, de s’attaquer à l’influence de la restauration rapide sur les jeunes. En effet, les adolescents sont de plus en plus touchés par le fléau grandissant qu’est l’obésité. A l’appui de la proposition politique, une étude américaine démontre que la présence de fast-foods à proximité des établissements scolaires augmente de 5% l’obésité infantile. L’amendement a été rejeté hier. En effet, il ne concernait que les grandes enseignes alors que des sandwicheries et des boulangeries s’implantent tout autant dans le périmètre de 200 mètres et proposent des produits tout aussi gras. Il a donc été jugé que les effets d’une telle mesure seraient discutables. Pourtant, elle aurait eu une portée symbolique importante. Le 2 juillet 2010 à 10:56 • Emmanuel Perrin
Facebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsApp#Bahamas, January 17, 2018 – Nassau – The two number one English speaking destinations in the Caribbean have been put on blast by America when it comes to safety and security and satisfaction and now both countries are in damage control mode. The Bahamas at its popular Fish Fry at Arawak Cay has seen vendors apologize for any negative experiences and mirroring a message by the Bahamas Government to improve service as security is enhanced, especially for Tourists.In Jamaica, the Minister of Tourism Edmund Bartlett has launched a campaign. Minister Bartlett says the $3b in earnings and a record setting 2017 with 4.3 million guests landing on their shores is not to be trifled with. Bartlett on Saturday in Montego Bay at a food handlers workshop said Jamaica must curb the reports of visitor harassment so as not to see a reversal in the gains made.Visitor satisfaction in Jamaica was put at 60% despite the harassment issues noted in a US Advisory. the Bahamas also got that advisory, but it was more severe saying Fish Fry’s reputation for a down home experience was sullied by reports of crime.#MagneticMediaNews#BahamasgetsnegaiveUSadvisories#JamaicagetsnegativeUSadvisories#BahamasandJamaicadamagecontrol Related Items:#BahamasandJamaicadamagecontrol, #BahamasgetsnegaiveUSadvisories, #JamaicagetsnegativeUSadvisories, #magneticmedianews
Los Angeles-based b-to-b publisher Canon Communications has reduced its workforce by 10 percent, or about 30 people. The cuts were made in an effort to “bring staffing in-line with our adjusted revenue outlook,” chairman and CEO Charlie McCurdy told FOLIO:. “We set our fiscal budgets in August and by December, and through January, it became clear that we weren’t pacing at consistent levels. We needed to revisit the outlook and consider some cost-savings measures.”Some of those additional measures include renegotiating vendor contracts, pairing back circulation and cutting frequencies at several of its magazine products. Canon in previous years has seen significant growth: roughly 10 percent organically year-over-year, McCurdy said. In November, the company reported a 23 percent increase in revenue for its 2008 fiscal year. The company attributed the increase to operational growth and strategic acquisitions in both its events and publishing businesses. Publishing division revenues grew 15 percent last year while events division revenues increased 30 percent due, in part, to attendance and exhibitor gains at its traditional trade shows and the launch of new events like BIOMEDevice and MD&M Midwest. Events revenues make up more than 50 percent of the company’s overall revenue mix, according to McCurdy.Another growth area is digital media, which has seen an average of 25 to 30 percent growth per year, McCurdy said. This year, he projects digital will be up between 15 and 20 percent.
The crew of a seiner is okay after their fishing vessel capsized in the Prince William Sound earlier this week. The Auriga was seeking at shelter from a storm at the time of the incident.Download Audio
Power sector utilities NTPC and Power Grid Corporation of India Ltd. (PGCIL) gained more than 3 percent on the Bombay Stock Exchange (BSE) on Thursday morning, driving the rally on Sensex and Nifty. PGCIL was up 4.48 percent to Rs 198, while NTPC shares were trading 3.25 percent higher at Rs 170 apiece.A few days ago, PGCIL had awarded a $640 million contract to ABB for 1,830-km (1,137-mile) power link in India to connect thermal and wind power plants with the country’s growing urban areas. The system will have the capacity to supply electricity to about 80 million people after completion in 2019, according to ABB. Read: India’s consumer inflation for December estimated at 3.6%, says DBS BankThe BSE Sensex was trading at 27,248, up 108 points, or 0.40 percent, while the NSE Nifty was up 25 points at 8,405. The day would be action-packed for markets for two reasons — the government will be releasing December 2016 provisional data for consumer (retail) inflation after trading hours and IT software services company Tata Consultancy Services (TCS) will be declaring its December quarter results. TCS shares were trading flat at Rs 2,317 apiece.Power generation details for December 2016The Central Electricity Authority (CEA) said that conventional power generation for December 2016 rose 6.18 percent YoY spanning thermal, hydro and nuclear energy. In case of thermal, the increase was 7.04 percent. The overall power generation for the April-December 2016 period was up 5.1 percent when compared to power generated during the corresponding period last financial year, according to the CEA.Rupee gainsThe Indian rupee opened 17 paise higher at 68.15 to the US dollar on Thursday.Benchmark bond yieldOn Wednesday, the yield on government debt due in September 2026 lost marginally to close at 6.39 percent.Earlier, in its pre-opening note, Geojit BNP Paribas Financial Services had said that Indian stock markets would open on a higher note tracking their Asian counterparts. “On Thursday, Asian markets opened on a mixed note. Japan’s Nikkei is down by around 0.9% and Shanghai down 0.08%. Indian markets are expected to open on a positive note tracking SGX Nifty, which is indicating up 0.33%, will watch India’s IIP and CPI data today.”
In the age before ubiquitous WiFi and online gaming, trading Pokemon was a complicated endeavor. Still, you had to trade with someone. One of the trademark features of Pokémon games for the Game Boy is that you can only “collect ’em all” by trading with someone who had a different version of the game. Good luck finding anyone still playing the first-generation games now, but coder Pepijn de Voshas devised a system to trade Pokémon with himself using an Arduino. That’s handy.All you need for this project is a link cable, two Pokémon games from the first-gen (Red, Blue and Yellow), an Arduino, a Game Boy (original, color, or Advanced), and some patience. Rather than plugging the Game Boy into a second Game Boy, you connect it to the Arduino. Modding the cable will probably take a little effort, though. When you enter trading mode, the Arduino mimics the trading protocol of a Game Boy and can be used to trade a single Pokémon.The Pokémon you trade to the Arduino is stored in EEPROM memory, which allows you to swap cartridges in the Game Boy and then initiate another trade. Just like that, you’ve gotten a Pokémon from one version of the game to another without a second Game Boy or a friend. Unless you consider the Arduino your friend.Pepijn de Vos has made the code available on GitHub for anyone to peruse and install on an Arduino for a little solo trading. While it was designed to work with first-generation games, the second-gen (Silver, Gold, Crystal) use the same trading protocol. It might work there as well, but no promises. This is not exactly an officially supported process.
Free Workshop | August 28: Get Better Engagement and Build Trust With Customers Now This hands-on workshop will give you the tools to authentically connect with an increasingly skeptical online audience. January 9, 2019 5 min read Opinions expressed by Entrepreneur contributors are their own. It’s just another day at work: Spreadsheets, conference calls and emails abound. Come noon, and you can’t help but take a quick break. Then, something happens: A sneaky push notification on your mobile catches your glimpse: A friend of yours has uploaded a video that’s getting a lot of attention.Related: 5 Video Marketing Trends You Should Follow in 2019Smitten with curiosity, you click on the link, and the next thing you know, it’s 1:30 and you’re already behind on your schedule. Don’t feel bad, though; we’ve all been there. If the sheer irresistibility of videos were its only criterion, Youtube could have gone with the tagline “No one can watch just one.” Certainly, the statistics point in that direction …One-third of online activity is spent watching videos, according to the Wordstream blog. By 2020, video will make up 80 percent of all consumer internet traffic, according to the Cisco Visual Networking Index. 59 percent of executives said they’d rather watch a video than read text according to the Wordstream blog.Viewers retain 95 percent of a message when they watch a video, as compared to 10 percent when they’re reading it in text, Wirebuzz wrote. Facebook videos receive 135 percent more organic reach than a photo, according to the Buffer blog. Now, the irony that you’re reading about how effective video is isn’t lost on me. For, clearly, video works, and for a good reason too. As humans (and pre-humans), we have been visual creatures for who knows how many millions of years; and we’re attuned to visuals far more than than text, which we only became acquainted with some 10,000 years ago.Related: 5 Incredibly Simple Strategies to Help You Win With Video MarketingYet, today, in the 21st century, video’s irrestistability isn’t all you have to put into it to make your business soar. Here are some video hacks that will take your website to new heights in 2019:Use videos on your landing pages.Why tell your visitors what you have to offer when you can show them all it can do? When viewers watch a (good) video, they usually want to finish it before moving to something else. EyeView digital found that videos on landing pages can increase conversions by 86 percent, which is why videos make the ideal content for getting more subscribers or sales.Not only does a video presentation with a powerful voice convince people to listen, but it gets them to stay longer, as well. A well put-together video sales pitch can also engender trust in your brand, as it will give you more creative space to play with.Use videos on your product pages.Seeing a product live in action is better any day than reading about it in a long paragraph filled with jargon and marketing-speak. Check out these examples of videos being used for promoting products for some ideas.Use VR/360 content.Video, like any other medium, sees frequent iterations, and brands that leverage those advancements can reap rich dividends. VR happens to be one of them. Despite naysayers, virtual reality, including “360 videos,” continues to gain market share. While, a few years ago, 360 content was fairly expensive to create, these days it can be made on a low budget, as well.Certainly, 360 cameras are the preferred medium for shooting such content, but you can easily make such videos with lesser equipment, as well.Migrate to HTML5.HTML5 is extremely searchable and makes it easy to implement both native mobile support and full browser support. HTML5 also brings numerous advantages that are hard to ignore, especially for videos.Users need not have any special plugins installed on their browsers to view HTML5 videos, either. In fact, almost every browser has default play, pause, seek and volume functions. However, if you wish to harness more advanced functions, you can look into dedicated html5 video players.Insert lead-capture forms directly into your videos.It’s nice enough to insert videos directly into a landing page, but wouldn’t it be cooler if you could just collect leads as a presentation is playing? That’s totally possible. Hubspot offers a lead-collection form for videos that can be used to capture leads from within them. Wistia even found that inserting a lead-capture form during the first 10 percent to 20 percent of your video yields a 38 percent to 43 percent increase in conversions.Use a human face as the thumbnail.More specifically, use a smiling human face, or one expressing an emotion that goes with the subject line. Doing so not only humanizes the content, it builds familiarity and trust; and the expression itself will resonate with the audience, which in turn will generate curiosity.Play around with autoplay.Turning a video on without the user’s permission is a slippery slope; however, this does make sense in some cases. For instance, brand -building videos on home pages that turn on automatically are becoming quite common. Youtube has gone with a default autoplay option for its videos as well.Related: 5 Low-Cost Ways to Get Started With Video MarketingFinal thoughtsWhile simply using videos as content is smart, remember: People know this, and chances are that quite a few of your competitors are already trying this out. Using out-of-the-box strategies therefore can help you institute that much needed edge in your marketing efforts. Enroll Now for Free
News | Magnetic Resonance Imaging (MRI) | June 01, 2016 New MRI Technology Shows Positive Results in Early Alzheimer’s Detection Targeted contrast agent from Alzeca Biosciences visualizes beta-amyloid deposition on conventional MRI before onset of symptoms Technology | Interventional Radiology | August 16, 2019 Profound Medical Receives U.S. FDA 510(k) Clearance for Tulsa-Pro Profound Medical Corp. announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to… read more News | Magnetic Resonance Imaging (MRI) | August 01, 2019 | Jeff Zagoudis, Associate Editor FDA Issues Draft Guidance on Medical Device Safety in MRI Environment The U.S. Food and Drug Administration (FDA) issued a new draft guidance titled Testing and Labeling Medical Devices for… read more News | Stroke | August 16, 2019 Mobile Stroke Unit Gets Patients Quicker Treatment Than Traditional Ambulance Every second counts for stroke patients, as studies show they can lose up to 27 million brain cells per minute…. read more Technology | Contrast Media | August 05, 2019 Bracco Receives FDA Approval for Varibar Thin Liquid for Oral Suspension Bracco Diagnostics Inc. announced U.S. Food and Drug Administration (FDA) approval for Varibar Thin Liquid (barium… read more Technology | Neuro Imaging | August 07, 2019 Synaptive Medical Launches Modus Plan With Automated Tractography Segmentation Synaptive Medical announced the U.S. launch and availability of Modus Plan featuring BrightMatter AutoSeg. This release… read more News | Neuro Imaging | August 16, 2019 ADHD Medication May Affect Brain Development in Children A drug used to treat attention-deficit/hyperactivity disorder (ADHD) appears to affect development of the brain’s… read more News | Magnetic Resonance Imaging (MRI) | August 06, 2019 Canon Medical Introduces Encore Orian MR Upgrade Program Canon Medical Systems USA Inc. is helping to provide low-cost patient care solutions for its customers with the launch… read more News | Cardiovascular Ultrasound | August 07, 2019 Contrast Use in First Transthoracic Echocardiogram for Heart Failure Reduces Repeat Testing Heart failure is the fourth most common cause for all admission to U.S. hospitals, and it is the most common reason for… read more June 1, 2016 — Alzeca Biosciences announced successful preliminary results for ADx, its novel, proprietary diagnostic imaging technology. The technology is designed to enable diagnosis of Alzheimer’s Disease for the first time on conventional magnetic resonance imaging (MRI), providing results a decade or more before the onset of symptoms of cognitive decline.Successful development of ADx would make early and reliable Alzheimer’s testing available to millions, using scanning technology that is widely available, and at far lower cost and without the radiation of current positron emission tomography (PET) scans. Earlier detection of Alzheimer’s could revolutionize the treatment of the disease and vastly improve the efficiency of clinical trials for new therapies by identifying appropriate candidates for participation.Alzeca also is exploring the significant additional potential of the underlying platform of ADx, which can be modified to bind to different targets in the brain. With these modifications, the platform could be used to image and diagnose other serious neurodegenerative diseases, and ultimately be used as a drug delivery system for treating those conditions.In peer-reviewed studies, the ADx nanoparticle demonstrated the ability to carry an encapsulated agent across the blood-brain barrier to bind precisely to amyloid plaques in the brains of test mice. Researchers were then able to obtain precise, high-resolution images of those plaques using ordinary MR equipment. These results, along with successful preliminary toxicity studies, allow Alzeca to accelerate the development and testing of ADx, with the goal of beginning human clinical trials in 2018. In May, the company was awarded a $322,000 grant from the Alzheimer’s Drug Discovery Foundation (ADDF) to fund the next phase of testing of ADx in canine subjects.More than 27 million people suffer from Alzheimer’s disease today, and it is the sixth leading cause of death in the United States. By 2050, the disease could result in a $1.1 trillion annual cost to the U.S. healthcare system. Yet there is no cost-effective, readily available, reliable way to diagnose the disease before the onset of cognitive decline – which is when current Alzheimer’s therapies have traditionally been most effective. ADx has the potential to confirm an Alzheimer’s diagnosis, as well as to rule out such a diagnosis. Misdiagnosed dementia patients not only receive the wrong therapies, but the cost of treating a misdiagnosed patient adds $14,000 to the annual cost of treatment.Alzeca’s biodiagnostic platform is a nanoparticle that can carry an imaging marker or other “payload” and pass through the normally impenetrable blood-brain barrier. The outside of each nanoparticle is designed to bind precisely to specific target substances in the brain, delivering the payload to that target.ADx is the first product based on the platform. ADx carries an MRI agent as its payload and through a ligand targets the amyloid plaques that are the hallmark of the onset of Alzheimer’s disease, developing ten or more years before cognitive impairment. Once ADx is bound to the plaques, beta-amyloid, the hallmark of the disease in its earliest stages, can be imaged in high resolution using a standard MRI scan.MR scans are radiation-free, far less costly and more readily available throughout the world compared with the only current alternative, a PET scan. PET scans cost two to five times MRI scans and require radioactive imaging agents that preclude routine use, while ADx would permit physicians to track the patient’s condition over time and even screen for the disease.For more information: www.alzeca.com FacebookTwitterLinkedInPrint分享 Related Content Two brain metastases from primary lung cancer are contrast enhanced in the brain of a 61-year-old male. Speakers at AHRA 2019 will state that ProHance and other macrocyclic MR agents present a very low risk to patients. Images courtesy of Bracco Images of regions of interest (colored lines) in the white matter skeleton representation. Data from left and right anterior thalamic radiation (ATR) were averaged. Image courtesy of C. Bouziane et al. News | Image Guided Radiation Therapy (IGRT) | July 16, 2019 AAPM 2019 Features More Than 40 Presentations on ViewRay’s MRIdian MRI-guided Radiotherapy ViewRay Inc. announced that the company’s MRIdian System is the focus of more than 40 abstracts selected by the… read more Feature | Contrast Media | July 18, 2019 | By Greg Freiherr How To Manage Risk in the MR Suite Macrocyclic contrast agents have the best safety profile of all the magnetic resonance (MR) contrast media that are n read more Image courtesy of UTHealth McGovern Medical School
AirAsia touches down with NRL Touch Football partnershipAirAsia touches down with NRL Touch Football partnershipThe World’s Best Low-Cost Airline, AirAsia and NRL Touch Football (NRLTF) announced a new partnership that will see the airline become the Official Airline Partner of NRL Touch Football in Australia.As part of the deal, the airline will proudly carry the Australian Youth Touch Football teams to and from Kuala Lumpur for the upcoming Youth Touch World Cup in August.NRLTF Chief Executive Steve Mitchell said, “We’re very excited to welcome AirAsia to the touch football family.“AirAsia is a renowned global brand and a world leader in their category. It’s an exciting time to be working with them as they develop their brand in Australia,” he said.“This partnership is particularly significant for our Australian youth teams, solidifying our quest to make the sport more affordable for participants and their families.”AirAsia X Group Head of Commercial Barry Klipp said, “AirAsia and AirAsia X is pleased to welcome NRL Touch Football to our ever-growing list of #DARETODREAM sporting partnerships.“AirAsia is an airline that believes in helping people achieve their dreams, and like sport is driven through hard work and determination. To inspire and enable these young Australians to discover their full potential as part of the Youth Touch World Cup in August this year is fantastic.“We look forward to welcoming the Australian youth teams on-board next month for the Youth World Cup.”AirAsia operates more than 60 services per week from Australia to its hub in Kuala Lumpur Malaysia, with onward connections to more than 130 destinations across Southeast Asia, the Middle East, and the US. AirAsia also operates the only wide-body A330 service between the Gold Coast and Auckland daily.To book your airfares for the World Cup or your next holiday, visit www.airasia.comSource = AirAsia
From June 20, members of the Flying Blue and Le Club AccorHotels loyalty programmes will be able to enjoy Miles+Points, an innovative opportunity to earn simultaneously points and miles while travelling with both companies: Earn Miles for your hotel stay and Points for each flight Convert Miles and Reward Points for even more ways to redeemAccor Group and the Air France-KLM Group are strengthening their existing partnership by offering, for the first time in the European travel industry a dual reward scheme to their entire global loyalty customer base.Every time customers travel on a flight marketed and operated by Air France and/or KLM, or stay a night at an Accor hotel, they will now simultaneously earn both Flying Blue Miles and Le Club AccorHotels Reward points.To take advantage of the Miles+Points service, members must link their accounts on www.flyingblue.com or on Le ClubAccorHotels website. After registering, customers will earn Flying Blue Miles and Le Club AccorHotelsReward Points automatically when flying with Air France and/or KLM or staying in a Le Club AccorHotels participating hotel.This new, strengthened partnership offers customers more opportunities to earn and redeem. It allows both the Air France-KLM Group and Accor Group to reward their members across more stages of their journey.“Meeting and exceeding customer expectations is our goal,” said Benjamin Smith, CEO Air France-KLM. “Adding more options to earn and redeem Flying BlueMiles was a key driver for the development of Miles+Points and we are glad we could develop this together with our partner Accor, for the benefit of our joint customers. We aim to position Flying Blue as a leading airline loyalty programme by continuing to enrich the customer journey at every step.”Sebastien Bazin, Chairman and Chief Executive Officer of Accor stated, “The partnership between Air France-KLM and Accor has been enhanced for the benefit of our most loyal members. It brings together two formidable players in global tourism and rewrites the rules of loyalty building. The radical transformation of Accor’s lifestyle loyalty programme, embodied by the future brand ALL – Accor Live Limitless – will bring to life our ‘augmented hospitality’ strategy and extend beyond mere hospitality and into the day-to-day lives of its members. This major partnership will contribute to realising this promise, leveraging the international footprint of both Groups.”